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Antioangiogenic Therapy Screen capture

Module Six

Practical Considerations in
Patient Management Involving Antiangiogenic Therapy

Release Date
22 February 2011

Expiration Date
22 February 2012
   
Sponsorship Statement
This activity is sponsored by prIME Oncology.
Accreditation Statement
prIME Oncology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation Statement
prIME Oncology designates this enduring Internet-based activity for maximum of 0.5 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Faculty
Artur Katz, MD
Sirio Libanes Hospital
São Paulo, Brazil

Mark Kozloff, MD
Ingalls Hospital
Harvey, Illinois, United States
Target Audience
This educational activity is designed for medical oncologists and other healthcare providers involved and/or interested in the practical considerations of antiangiogenic therapy in the management of solid tumors.
Overview
This module is the last in a six part series in which international oncology experts engage in discussion and review updated clinical information regarding the utility of antiangiogenic therapy in the management of solid tumors. Participants may view an expert discussion and are provided with downloadable reference slides.
Educational Objectives
Upon completion of this educational activity, participants should be able to:
  • Identify appropriate chemotherapy backbones for combination therapy with antiangiogenic agents
  • Assess clinical endpoints for clinical trials investigating antiangiogenic therapies
  • Discuss the optimal duration of antiangiogenic therapy
  • Explain the management of adverse events associated with antiangiogenic therapy
  • Evaluate the appropriate clinical implementation of antiangiogenic agents based on available data
  • Summarize the potential role of antiangiogenic agents for specific malignancies based on the clinical development programs and available preclinical data
Method of Participation
There are no fees for participation in and receiving continuing medical education (CME) credits for this activity. In order to receive credit, participants must successfully complete the online post test and activity evaluation. Your participation in this CME activity will be recorded in prIME Oncology’s database. However, upon request, your CME credit certificate will be emailed to you.

Links to the post tests are available on the activity selection page and video player pages.
Technical Requirements
To participate in this activity, your computer should have a processor the equivalent of Intel Pentium II 450 MHz or faster, with 128 MB of RAM and a connection to the Internet.

Estimated time to complete activity: 30 minutes
Support Statement
Support for this activity has been provided by an unrestricted educational grant from F. Hoffmann-La Roche, Ltd.
Disclosure of Conflicts of Interest
In accordance with the ACCME standards for Commercial Support, educational activities sponsored by prIME Oncology must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, and planning committee members participating in a prIME Oncology–sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.

FACULTY
Dr Katz has disclosed that he has received CME consulting fees from F. Hoffmann-La Roche Ltd, Pfizer Inc, and AstraZeneca Pharmaceuticals. Also he received fees for non-CME services from F. Hoffmann-La Roche Ltd, Pfizer Inc, and AstraZeneca Pharmaceuticals. None of these relationships will impact his ability to present an unbiased discussion.

Dr Kozloff has disclosed that he has received CME consulting fees from F. Hoffmann-La Roche Ltd, and Genentech. He also received fees for non-CME services from F. Hoffmann-La Roche Ltd, and Genentech. None of these relationships will impact his ability to present an unbiased discussion.

PLANNERS
Nathan Kelly, PhD (clinical) – no real or apparent conflicts of interest
Trudy Stoddert, ELS (editorial) – no real or apparent conflicts of interest
Susan H. Yarbrough, CCMEP (compliance) – no real or apparent conflicts of interest
Disclosure of Unlabeled Use
Participants have implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

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