On behalf of Dr Nadia Harbeck, meeting chairman, we are pleased to invite you to the Expert PracticeSM in Breast Cancer meeting in
Berlin, Germany, on 7 February 2009.

During this case-based meeting, leaders in the field discuss clinical issues encountered daily with participants in an interactive format.


Delegates will receive:

• Round trip economy air or train transportation.
• Hotel accommodation for 6 February. If no return flight available after the meeting, hotel accommodation will also be provided Saturday, 7 February.

Chair:
          Nadia Harbeck, MD, PhD – Germany
Speakers:
          Ahmad Awada, MD, PhD – Belgium
          Jacques Bonneterre, MD, PhD – France
          Michael Gnant, MD, PhD – Austria
          Paolo Pronzato, MD – Italy
          Julie Doughty, MD, FRCS – United Kingdom

Friday, 6 February 2009
20.00	Reception followed by Buffet Dinner
Saturday, 7 February 2009
08.00	Breakfast
09.00	Welcome and Introduction Nadia Harbeck, MD, PhD, Technical University of Munich, Munich, Germany Bojana Pajk, MD, PRIME Oncology Lee Lokey, MD, PRIME Oncology
09.20	Case #1 HER-2 Amplified Early Breast Cancer: Choosing the Most Effective Adjuvant Therapy Jacques Bonneterre, MD, Centre Oscar Lambret, Lille, France
09.50	Case #2 Endocrine Responsive Early Breast Cancer: Decision Making for the Postmenopausal Patient Julie Doughty, MD, University of Glasgow, Glasgow, UK
10.20	Case #3 Targeted Therapy for HER-2 Positive Metastatic Breast Cancer Ahmad Awada, MD, PhD, Jules Bordet Institute, Brussels, Belgium
10.50	Break
11.10	Case #4 Neoadjuvant Therapy in Endocrine Responsive HER-2 Negative Breast Cancer: Multidisciplinary Management Julie Doughty, MD, University of Glasgow, Glasgow, UK Paolo Pronzato, MD, S. Andrea Hospital, La Spezia, Italy Michael Gnant, MD, Medical University of Vienna, Vienna, Austria (commentary)
11.50	Debate In the Near Future Evidence from Randomized Clinical Trials Will Support Inclusion of Zoledronic Acid as a Component of Adjuvant Systemic Therapy for Early Breast Cancer       Pro: Michael Gnant, MD, Medical University of Vienna, Vienna, Austria       Contra: Paolo Pronzato, MD, S. Andrea Hospital, La Spezia, Italy
12.20	Ask the Experts: An Interactive Discussion
12.40	Lunch
13.40	Case #5 Breast Cancer Progression After Adjuvant Chemotherapy: What is the Best Approach? Ahmad Awada, MD, PhD, Jules Bordet Institute, Brussels, Belgium
14.10	Case #6 Breast Cancer Management During Pregnancy: A Difficult Challenge Nadia Harbeck, MD, PhD, Technical University of Munich, Munich, Germany
14.40	Ask the Experts: An Interactive Discussion
15.00	Concluding Remarks Nadia Harbeck, MD, PhD, Technical University of Munich, Munich, Germany