Oncology Clinical Trial Report in Melanoma - prIME Oncology
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Oncology Clinical Trial Report in Melanoma

Putting Key Findings From the 2018 European Oncology Congress Into Practice

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View CME-certified poster presentations and downloadable slides covering the most up-to-date clinical trial data on melanoma from the 2018 European Oncology Congress in Munich.

Interactive Presentation

Interactive Presentation

Downloadable Slides

Downloadable Slides

CME

CME

1.5 AMA PRA Category 1 Credit(s)

Release Date

Release Date

Apr 15, 2019

Expiration Date

Apr 15, 2020

Reinhard Dummer, MD

Abstract #LBA44: Overall survival at 4 years of follow-up in a phase 3 trial of nivolumab plus ipilimumab combination therapy in advanced melanoma (CheckMate 067)

Featured Expert: Reinhard Dummer, MD

Celeste Lebbé, MD

Abstract #LBA47: Initial results from a phase 3b/4 study evaluating two dosing regimens of nivolumab (NIVO) in combination with ipilimumab (IPI) in patients with advanced melanoma (CheckMate 511)

Featured Expert: Celeste Lebbé, MD

Paolo A. Ascierto, MD

Abstract #1244O: KEYNOTE-022 Part 3: Phase 2 randomized study of 1l dabrafenib (D) and trametinib (T) plus pembrolizumab (Pembro) or placebo (PBO) for BRAF-mutant advanced melanoma

Featured Expert: Paolo A. Ascierto, MD

Omid Hamid, MD

Abstract #1248PD: Efficacy of pembrolizumab (Pembro) in patients (Pts) with advanced melanoma with stable brain metastases (BM) at baseline: A pooled retrospective analysis

Featured Expert: Omid Hamid, MD

Christian U. Blank, MD, PhD

Abstract #LBA42: OpACIN-neo – A Multicenter Phase 2 Study to identify the Optimal neo-Adjuvant Combination scheme of Ipilimumab (IPI) and Nivolumab (NIVO)

Featured Expert: Christian U. Blank, MD, PhD

Antoni Ribas, MD, PhD

Abstract #LBA45: Poster Discussion Session: Phase 1b/2, Open Label, Multicenter, Study of the Combination of SD-101 and Pembrolizumab in Patients with Advanced Melanoma who are Naïve to Anti-PD-1 Therapy

Featured Expert: Antoni Ribas, MD, PhD

  • Paolo A. Ascierto, MDNational Tumor Institute - Fondazione G. Pascale
    Naples, Italy
  • Christian U. Blank, MD, PhDNetherlands Cancer Institute
    Amsterdam, the Netherlands
  • Reinhard Dummer, MDUniversity of Zurich Hospital
    Zurich, Switzerland
  • Omid Hamid, MDThe Angeles Clinic and Research Institute
    Los Angeles, California, United States
  • Celeste Lebbé, MDHôpital Saint Louis
    Paris, France
  • Antoni Ribas, MD, PhDUCLA Jonsson Comprehensive Cancer Center
    Los Angeles, California, United States

This activity is specifically designed for physicians, nurses, and other clinicians who are cancer specialists.

After successful completion of this educational activity, participants should be able to:

  • Identify clinical trial data presented at 2018 European Oncology Congress in Munich
  • Incorporate new findings presented in Munich into patient treatment regimens, where applicable

This educational activity is supported by grants from Bayer HealthCare Pharmaceuticals, Inc.; Bristol-Myers Squibb; and Merck and Co, Inc.

Continuing Education

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and prIME Oncology. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Provider

This activity is jointly provided by Postgraduate Institute for Medicine and prIME Oncology.

Disclosure Information

Method of Participation

There are no fees for participating in and receiving CME credit for this activity. In order to receive credit, participants must successfully complete the online activity evaluation. Your participation in this CME activity will be recorded in prIME Oncology’s database and in your My prIME account. You can download your certificate as needed. Technical requirements may be found under the Terms of Use.

Estimated time to complete activity: 1.5 hours

To contact Postgraduate Institute for Medicine please visit www.pimed.com.

Disclosure of Relevant Financial Relationships

Postgraduate Institute for Medicine (PIM) and prIME Oncology require instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. PIM is committed to providing its learners with high quality activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouses/life partners have with commercial interest related to the content of this activity:

Dr Blank has disclosed that he received consulting fees from Bristol-Myers Squibb, Genmab, GlaxoSmithKline, Lilly, Merck Sharp & Dohme, Novartis, Pfizer, and Roche. He also disclosed independent contracting for Bristol-Myers Squibb, Nanostring, and Novartis. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.

Dr Dummer has disclosed intermittent, project-focused consulting and/or advisory relationships with Amgen, Bristol-Myers Squibb, Merck Sharp & Dohme, Novartis, Pierre Fabre, Roche, Sanofi, Sun Pharma, and Takeda. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.

Dr Hamid has disclosed that he has received consulting fees from Amgen, Bristol-Myers Squibb, Merck, Novartis, and Roche/Genentech. He also received honoraria for promotional speaker’s bureaus from Amgen, Array Biopharma, Bristol-Myers Squibb, Novartis, and Roche/Genentech. He also disclosed independent contracting for his institution for AstraZeneca, Bristol-Myers Squibb, Celldex, Immunocore, Incyte, MedImmune, Merck, Merck Serono, Novartis, Pfizer, Rinat, and Roche/Genentech. Furthermore, he disclosed membership on advisory committees or review panels for Amgen, Bristol-Myers Squibb, Merck, Novartis, and Roche/Genentech. He has been speaking and teaching for Amgen, Array Biopharma, Bristol-Myers Squibb, Novartis, and Roche/Genentech. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.

Dr Lebbé has disclosed that she has been on advisory boards for Aventis, Bristol-Myers Squibb, Merck, Merck Sharp & Dohme, Novartis, and Roche. Furthermore, she has been speaking and teaching for Bristol-Myers Squibb. She has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in her presentation.

Dr Ribas has disclosed board membership with PACT Pharma. He received consulting fees from Amgen, Bristol-Myers Squibb, Chugai, Genentech, Merck, Merck Sharp & Dohme, Novartis, and Roche. Furthermore, he disclosed ownership interest in Advaxis, Arcus, Bioncotech, Compugen, CytomX, Five Prime, FLX-Bio, ImaginAb, Isoplexis, Kite-Gilead, Lutris, Merus, PACT Pharma, Rgenix, and Tang Therapeutics. He has agreed to disclose any unlabeled/unapproved uses of drugs or products referenced in his presentation.

Postgraduate Institute for Medicine Planners and Managers have disclosed no relevant financial relationships.

The employees of prIME Oncology have disclosed:

  • Angela Zimmermann, PhD (scientific content manager) – worked on non–CME certified projects in the last 12 months supported by AstraZeneca, Merck, Novartis, and Pfizer
  • Susan McKinney (editorial content reviewer) – no relevant financial relationships

Disclosure Regarding Unlabeled Use

This activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration or European Medicines Agency. Please refer to the official prescribing information for each product discussed for discussions of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.