Reduced Survival with Higher Radiation Dose for Non-Hodgkin Lymphoma

Prior to hematopoietic stem cell transplant (HSCT), patients with non-Hodgkin lymphoma (NHL) typically undergo total body irradiation and chemotherapy as part of a conditioning regimen. In order to reduce the risk of relapse following HSCT, some patients with higher risk disease may receive higher doses of radiation. However, according to a study presented recently at […]

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Watch-And-Wait An Effective Treatment Strategy in Rectal Cancer

For patients with early stage rectal cancer who achieve complete response following chemoradiotherapy, next steps for treatment are not always clear. While some believe patients should undergo total mesorectal excision, others prefer a more conservative strategy of active surveillance, or “watch-and-wait.” Unfortunately, there are limited data on the long-term impact of watch-and-wait on patient outcomes. […]

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Therapy-Associated Polyposis in Younger Patients with Cancer

In recent years, therapy-associated polyposis (TAP) has emerged as a potential side effect of cancer therapy in children and young adults, potentially associated with an increased risk of gastrointestinal (GI) cancer later in life. However, only 8 cases of TAP in cancer survivors have been reported and the link between cancer treatment and polyposis is […]

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Cancer “Victory Bell” May Cause Treatment-Related Distress

Ringing the “victory bell” to signal the end of cancer treatment is considered a rite of passage for survivors, associated with successful treatment. However, this ceremony is controversial, with some patient advocates suggesting it may cause feelings of anger or depression in patients with metastatic disease who require chronic treatment. Now the first-ever prospective controlled […]

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Improving Outcomes for Bone Marrow Transplant Recipients

Bone marrow transplant is a common treatment option for many patients with hematologic malignancies, but these transplants have historically been associated with significant morbidity and mortality. However, a retrospective analysis published in the Annals of Internal Medicine shows that outcomes for patients who receive bone marrow transplants have improved substantially in recent decades. The analysis […]

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Atezolizumab and Bevacizumab Improve Quality of Life in HCC

While patients with unresectable hepatocellular carcinoma (HCC) have historically received first-line treatment with sorafenib, results from the IMbrave150 suggest that the combination of the PD-L1 inhibitor atezolizumab with the angiogenesis inhibitor bevacizumab may be a more effective treatment option. Initial results from this randomized, phase III trial (N = 501) showed a significant overall survival […]

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More than 10% of Cancer Cases Caused by Infection

Several infectious agents are known to be associated with increased risk of developing cancer. According to a study recently published in Lancet Global Health, the rate of cancer associated with infection is higher than expected. The study used the GLOBOCAN 2018 database of cancer incidence and mortality rates to evaluate specific cancer types known to […]

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Dietary Changes Do Not Slow Rate of Prostate Cancer Progression

Despite suggestions by current clinical guidelines that outcomes, including rate of clinical progression and mortality, are improved in patients with prostate cancer eating vegetable-rich diet, a new study has found no such correlation. The randomized, controlled Men’s Eating and Living (MEAL) study evaluated the impact of a vegetable-rich diet compared to active surveillance in 443 […]

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Increasing Rates of Early-Onset Gastric Cancer in the United States

Gastric cancer is a severe malignancy associated with a poor prognosis that most commonly occurs in patients over the age of 70. Although gastric cancer is the third most common cancer in the United States, rates of this malignancy have been in decline in recent years due to increased understanding of risk factors and efforts […]

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